DreamPirates logo DreamPirates
health

Next Generation Immune Checkpoint Inhibitors and Stimulators Market, 2030

- By Stella01wilson
Publish Date : 2021-04-30 07:03:38
Next Generation Immune Checkpoint Inhibitors and Stimulators Market, 2030

Roots Analysis is pleased to announce the publication of its recent study, titled, “Next Generation Immune Checkpoint Inhibitors and Stimulators Market, 2020-2030.” 

The report features an extensive study of the current market landscape, offering an informed opinion on the likely adoption of these therapies over the next decade. It features an in-depth analysis, highlighting the capabilities of various stakeholders engaged in this domain. In addition to other elements, the study includes:

  • A detailed assessment of the current market landscape of drug developers engaged in the development of next generation immune checkpoint modulators.
  • A detailed analysis of more than 590 completed, ongoing and planned clinical studies of next generation immune checkpoint inhibitors and stimulators.
  • Detailed profiles of developers of next generation immune checkpoint modulators (shortlisted on the basis of the number of pipeline products).
  • An in-depth analysis of more than 490 grants that have been awarded to research institutes engaged in next generation immune checkpoint therapy-related projects.
  • An analysis of the partnerships that have been established in this domain, in the recent past.
  • A competitiveness analysis of biological targets, featuring insightful pictorial summaries and representations.
  • An analysis of the initiatives of big biopharma players engaged in this domain.

A detailed market forecast, featuring analysis of the current and projected future opportunity across key market segments (listed below)

Next Generation Immune Checkpoint Inhibitors and Stimulators Market Size by 2030

Cancer is known to be one of the leading causes of death worldwide, accounting for 0.6 million deaths in 2019, in the US alone. The World Health Organization has estimated the number of new cancer cases to rise by 70% over the next 20 years, across the globe. Conventional treatment options, such as chemotherapy, surgery and radiation therapy, are still considered as the current standard of care. However, their efficacy is severely limited, especially when it comes to treating late-stage cancers. Moreover, the non-specific and highly toxic nature of chemotherapy and radiation therapy, are known to have a significant adverse impact on patients’ quality of life. There are several targeted anti-cancer therapies that are available in the market and many are presently under development. Of these, immune checkpoint therapies have shown a lot of promise as viable and potent treatment options, capable of preventing tumor cells from evading immune surveillance. In 2011, Bristol-Myers Squibb’s Yervoy® (ipilimumab), an anti-CTLA-4 monoclonal antibody, became the first FDA approved immune checkpoint inhibitor which was designed for the treatment of metastatic melanoma. Yervoy®, along with other first generation immune checkpoint inhibitors (targeting PD-1/PD-L1 and CTLA-4), soon demonstrated the ability to substantially prolong the lives of patients suffering from advanced stage tumors. However, despite the success of PD 1 / PD-L1 inhibitor drugs, there was a notable amount of resistance to treatment reported in certain groups of patients, which compromised the therapeutic potential of this relatively novel class of therapeutics. 

Over the years, significant strides have been made in immune checkpoint modulation research, revealing several inhibitory (LAG-3, TIM-3, TIGIT, VISTA and B7-H3) and stimulatory receptors (OX40, ICOS, GITR, 4-1BB and CD40), which are now being exploited for development of next generation immune checkpoint-based therapies. Moreover, clinical studies of combinatorial immune checkpoint blockade / co-stimulation, involving the newly identified checkpoints and known immune checkpoint inhibitor therapies, have demonstrated the potential to further augment therapeutic benefits. It is worth highlighting that these molecules have also shown to be capable of regulating immune tolerance and preventing / treating autoimmune disorders. Therefore, backed by promising clinical results and expanding applicability of therapies being investigated in late stages of development, the immune checkpoint inhibitors and stimulators market is poised to witness substantial growth in the foreseen future.

Target Disease Indication

  • Breast Cancer
  • Chronic Lymphocytic Leukemia
  • Colorectal Cancer
  • Head and Neck Cancer
  • Lung Cancer
  • Lupus Nephritis
  • Melanoma
  • Multiple Myeloma
  • Primary Sjögren's Syndrome
  • Others

Target Immune Checkpoint

  • B7-H3
  • CD38
  • CD40
  • CD47
  • Others

Mechanism of Action

  • Inhibitory
  • Stimulatory

Therapeutic Modality

  • Monoclonal Antibody
  • Small Molecule

Type of Therapy

  • Monotherapy
  • Combination Therapy

Route of Administration

  • Intravenous
  • Subcutaneous
  • Others

Key Geographical Region

  • North America
  • Europe
  • Asia-Pacific and the Rest of the World

Key companies covered in the report

  • Bristol Myers Squibb
  • GlaxoSmithKline
  • Incyte
  • Novartis
  • Trillium Therapeutics

Get Customized Reports:

https://www.rootsanalysis.com/reports/303/request-customization.html    

About Roots Analysis

Roots Analysis is one of the fastest growing market research companies, sharing fresh and independent perspectives in the bio-pharmaceutical industry. The in-depth research, analysis and insights are driven by an experienced leadership team which has gained many years of significant experience in this sector. If you’d like help with your growing business needs, get in touch at [email protected]

Contact Information

Roots Analysis Private Limited

Gaurav Chaudhary

+1 (415) 800 3415

[email protected]



Category : health

BHAKTI – AN ASSOCIATION OF THE HEART

BHAKTI – AN ASSOCIATION OF THE HEART

- Bhakti is viewed as the best of the Yoga Trainer Course approaches since it straightforwardly contacts the heart. It is likewise the simplest to follow


Instructions About Avaya 71300X Exam Preparation

Instructions About Avaya 71300X Exam Preparation

- With the internet becoming place. about the new deal that contained a provision that seniority by on your own would not decide trainer assignments or transfers.


Attaining Dental School Admission Information

Attaining Dental School Admission Information

- Here is how you can learn more about dental school admission so that you can be better prepared when it is time to go to school.


Why we Use of Tibetan singing bowl

Why we Use of Tibetan singing bowl

- Buy Tibetan singing bowl, positively press the going with a little sledge in a round development against the bowls outside edge or edge.